Ti-Life
Technology

Ti-LifeTECHNOLOGY

Spineart developed a specific algorithm to enhance the classic additive manufacturing process resulting in a unique bone-like matrix: Ti-LifeTECHNOLOGY.

Ti-LifeTECHNOLOGY achieves a geometry that would not be possible through classic manufacturing processes. The result is a Titanium porous structure similar to natural trabecular bone.

 

Material

Over the last decade, Titanium biocompatibility has been demonstrated and accepted by the scientific community. Unlike polymer materials (PEEK), the Titanium porous structure and roughness facilitate bone tissue ingrowth1-2-3.

 

Architecture

Additive manufacturing produces highly cohesive device which differentiates the Ti-LifeTECHNOLOGY from non-porous surface treatments and coating techniques (4). The micro-porous scaffold mimics the cancellous bone structure and features interconnected pores (diameter between 0.6 and 0.7mm), with an average of 70-75% overall porosity, that enables cell colonization6. As a comparison, natural bone features around 60% porosity with pore diameter ranging from 0.3 and 1.5mm5-6-7.

 

Properties

Ti-LifeTECHNOLOGY contributes to a unique osteoconductive environment designed to promote bone in-growth.

Ti-LifeTECHNOLOGY allows to design devices featuring an overall reduced density to optimize the medical imaging performances and post-operative evaluations.

Ti-LifeTECHNOLOGY features a rough surface for primary stability within the endplates.

1In Vivo performance of selective electron beam-melted Ti-&Al-4V structures

Ponader, S et al., 2010

2Evaluation of biological properties of electron beam melted Ti6al4V implant with biomimetic coating in vitro and in vivo.

Li, X et al., 2012

3Porous titanium-6 aluminium-4 vandium cage has better osseointegration and less micromotion than a poly-ether-ether-ketone cage in sheep vertebral fusion.

Yang, J. et al., 2014

4Does impaction of titanium-coated interbody fusion cages into the disc space cause wear debris or delamination?

Annette Kienle, MDa,*, Nicolas Graf, Dipl-Ing (FH)a, Hans-Joachim Wilke, PhDb

5Direct three-dimensional morphometric analysis of human cancellous bone: microstructural data from spine, femur, iliac crest, and calcaneus

Tor Hildebrand, Andres Laib, Ralph Müller, Jan Dequeker, Peter Rüegsegger

Journal of bone and mineral research. Volume 14, Number 7, 1999

6Porosity of 3D biomaterial scaffolds and osteogenesis

Vassilis Karageorgiou, David Kaplan

Biomaterials 26 (2005) 5474-5491

7Chapter 8 - Bone Mechanics

Tony M. Keaveny, Elise F. Morgan, Oscar C. Yeh

Standard handbook of biomedical engineering and design